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One of the last things you want to see in your garage is a bee's nest. Bees are opportunistic architects and will construct their elaborate hives wherever they can. Bees commonly build their nests in the corners of walls or similar protected spots in the garage. Having a bee's nest so close to you is problematic, as you can become the victim of a bee sting, which is particularly dangerous if you are allergic. Eliminating a nest is simply a matter of using the right product at the right time.
Wear gloves, a long-sleeved shirt, pants and boots. Approach the hive at dusk, when all of the bees are resting inside.
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Spray the nest with a ready-to-use insecticidal spray for bees. Most are simply sprayed directly onto the nest until it is saturated; however, read the directions on the label for best results.
Observe activity at the nest the following day. The bees are sufficiently eliminated if none are seen flying in and out of the nest. Spray the nest again at dusk at three-day intervals if you still see bee movement.
For a less-toxic; however, more risky approach, cover the nest with a thick, plastic bag at dusk wearing your protective clothing, then seal the bag shut. Pull the nest away from its site and either freeze it or place it in the sun. The harsh temperatures should kill the bees in about two days. Throw the bag into a sealed outdoor trash can for disposal.
Wear a facial mask to prevent inhaling the insecticide. Prevent bees from building nests in your garage by continually monitoring the wall corners and spraying or removing any beginnings of nests you detect.