What Medications Can Cause Leg Swelling?

Leg swelling occurs when there is an abnormal buildup of fluid in the legs. Swelling may be caused by medications. Some of these medications may include steroids, hormones, high blood pressure medicines, diabetes medicines and antidepressants.

  1. Steroids

    • Steroids are medicines which may be classified as anabolic-androgenic and corticosteroids. Anabolic-androgenic steroids may help repair the tissue-building process, while corticosteroids may help control inflammation.

    Hormones

    • Hormones act as the body's chemical messengers. Different types of hormones can cause different reactions such as effects on the mood, metabolism or reproduction.

    High Blood Pressure Medicines

    • High blood pressure medicines can relax the heart muscles and lower the blood pressure. Some of these types of blood pressure medications may include calcium channel blockers, alpha blockers and sympathetic nerve inhibitors.

    Diabetes Medicines

    • Diabetes is a chronic disease affecting blood glucose levels. Diabetes medicines can help patients control their blood glucose levels to reduce possible diabetic complications, including nerve damage and kidney disease.

    Antidepressants

    • Antidepressants are medications that may help regulate brain chemicals called neurotransmitters, which assist with brain function. Some of these antidepressants include tricyclics such as amitriptyline and desipramine.

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