Things You'll Need
Mouse traps or bait
Rubber or nitrile gloves
Plastic trash bags
Mice rarely build their nests in places that can be accessed easily; in some cases they build them in areas that can be potentially dangerous to the health of homeowners. Mouse nests in a furnace will not only spread the scent of mouse urine and feces throughout the home, but they can also cause a home fire. Add to that the fact that some mice carry the deadly Hantavirus and removing them is not an option, it's a necessity.
Look around all possible sources of water. Check for mouse droppings on or around the water heater, plumbing, refrigerator, dishwasher and washing machine.
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Place a common snap trap in each area where droppings are found baited with peanut butter. Place the trap perpendicular to the wall so that the mechanism snaps toward the wall. This will prevent them from being thrown clear of the trap.
Seal poison bait such as D-con in an envelope. Mice can smell and consume the bait through the paper. You can also visibly determine if the bait has been eaten.
Continue to monitor and replenish bait until you are sure that mice have been caught.
Clean the nest out with the air running. Spray all urine and droppings with a disinfectant and allow it to soak for 5 minutes. Wear rubber or nitrile gloves and paper towels to place all nest contents into a plastic garbage bag. Do not stir up dust by sweeping or vacuuming.
Keep mouse traps and bait out of reach of children and pets. Follow all label directions and warnings on all pest control products.