About Bextra

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Bextra is a non-steroidal anti-inflammatory used to treat osteoarthritis, rheumatoid arthritis and dysmenorrhea, but it was taken off the market due to liver toxicity, heart attack and allergic reaction. Discover the dangerous nature of Bextra with information from the CEO of a pharmacy company in this free video on medicine.

Part of the Video Series: Prescription Drugs & Side Effects
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Video Transcript

This is Lois Adams, and I'm President and CEO, and a consultant pharmacist with Freedom Pharmacy in Orlando, Florida. This segment is going to be about the drug Bextra which has been removed from the market. It is a member of the non-steroidal anti-inflammatory group, and is also a member of the Cox-2 inhibitor group. Other drugs were taken off the market, but Celebrex was able to be on. The drug is indicated or was indicated for the treatment of osteoarthritis and rheumatoid arthritis, and dysmenorrhea which is associated with painful menstrual cycle. There were 12.2 billion prescriptions written in 2004, so you can see how many people were actually on this drug. Many serious side effects came to to the fore such as liver toxicity, incidence of heart attack, allergic reactions, and and stroke and Bextra was link to all of these. The package indications only showed that you should not take this when you are pregnant, however the Pfizer did issue a very strong warning that there were other indications or or side effects from this. There was a class action suit filed against the manufacturer to withdraw the drug from the market. The manufacturer did withdraw it from the market in 2005, along with other members of this family. Celebrex was con was able to continue to resume sales. The thing that was very worrisome about this is that that the package insert that went to the professionals; the pharmacist and the physicians, showed only the issue about the pregnancy and none of the other strokes; however, Pfizer did know that that those side effects did occur, and they failed to report it to the general public. The drug is no longer on the market.


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