The touchpad software on Sony's Vaio series laptops includes an option to disable the device entirely. Whether you disabled the touchpad intentionally to use an external mouse, or the setting changed by accident, you'll need to re-enable it to use the touchpad again. If this setting does not fix an unresponsive touchpad, your Vaio may have faulty hardware or an incompatibility with a printer.
Controlling Your Computer
Without a working touchpad, you'll need to either plug in an external mouse or use the keyboard to navigate to the touchpad settings. If you don't have a mouse, use the arrow keys to browse and select items. "Tab" will switch between sections of windows. Press the space bar to toggle check boxes on and off and to expand nested menus. Pressing "Enter" will open the currently selected item or press a highlighted button.
From the Windows desktop, press the "Windows" key, type "Vaio Control Center" and press "Enter." Select and expand the "Keyboard and Mouse" section and then select "Pointing Device." Tab over to the "Enable" box and press "Space" to check it. Press "OK" or "Apply" to enable the touchpad. On some older Vaio models, you can find the Vaio Control Center options in the "VAIO Support Central" application by opening the "System Maintenance" tab and then the "System Information" tab.
Sony reports that occasionally, an installed but disconnected printer can cause a Vaio touchpad to stop working. In this case, plugging in the printer and turning it on should restore touchpad functionality. If this works, you'll need to either leave the printer connected, uninstall the printer or install newer printer drivers that resolve the conflict. Sony recommends contacting the printer's manufacturer for further support if you can't fix the incompatibility.
If nothing else works, your touchpad may simply be broken. Reboot your computer and press "F10" while the computer boots to launch VAIO Recovery. If the touchpad does not work even in this program, the hardware itself is likely defective. If it does work in recovery, you can try reinstalling the touchpad drivers or, as a last resort, using System Restore or reinstalling the operating system.
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