Radiesse Complications

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Radiesse contains the synthetic substance calcium hydroxylapetite, and Radiesse injections are an alternative to plastic surgery. Results typically last 12 to 18 months, and sometimes last up to three years. Most complications are rare.


Radiesse is applied to fill depressions below the eyes, and to treat skin folds and wrinkles. It also is useful for treating acne pitting. Some practitioners administer Radiesse for lip augmentation, although the manufacturers advise against it.


Pain is a common side effect of Radiesse, although topical or local anesthetic can control pain during the procedure. Injections in and around the lips tend to cause the worst pain, according to Derma Network.

Skin Irritation

Some patients experience bruising, swelling and redness, which usually disappears within 24 hours. Other possible complications that may last up to 48 hours include puffiness, minor pain, itching and discoloration.


Radiesse manufacturer BioForm Medical Inc., advises against using the product for lip augmentation because it tends to cause nodules there in some patients. These small bumps are calcium deposits resulting from a reaction to the substance, and they require surgical removal.


People who are prone to certain types of scars should not have Radiesse injections. Keloids and hypertrophic scars develop into raised nodules of scar tissue that can be red or pink.

Rare Complications

Rarely, Radiesse injections can lead to infection or an allergic reaction.

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