- Men and women may develop an allergic rash to Nonoxynol-9 that is red and irritating. A persistent rash called contact dermatitis may also develop.
- Urination problems such as painful and frequent urination, bloody urine and bladder pain may occur in women who develop a urinary tract infection following use of Nonoxynol-9.
- A stinging or burning sensation may develop during the use of a spermicide, indicating an allergic response. The spermicide should be removed immediately.
- Another common allergic response to spermicides is an itching sensation where the spermicide has come in contact with the skin.
- According to drugs.com, in rare cases, women can develop a case of allergic vaginitis when exposed to Nonoxynol-9 that results in rash, irritation and a whitish discharge.
- Allergic responses such as itching, irritation, stinging or burning could indicate an allergic reaction to latex rather than a spermicide.














