Cymbalta and Zoloft are two well-known medications generally prescribed for depression, but they differ significantly. The two antidepressants are often actively compared based upon their differences. For those seeking mental help through medication, it is important to know the details, differences and effects of each drug before deciding upon which one to take.
Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It is believed to correct the chemical imbalance of serotonin and norepinephrine in the brain by blocking its serotonin reuptake, which treats severe depression. It is also used for chronic pain disorder and those with diabetes who suffer from nerve damage pain.
Zoloft is a selective serotonin reuptake inhibitor (SSRIs) antidepressant. It used to treat depression, panic and anxiety disorders, post-traumatic stress disorders (PTSD), premenstrual dysphoric disorder (PMDD) and obsessive-compulsive disorder (OCD). Zoloft corrects the chemical imbalance of serotonin within the brain by increasing the levels of serotonin while blocking reuptake of serotonin.
Cymbalta comes in 20 mg, 30mg and 60 mg capsules, which are specifically designed for gradual time release. The generic name for Cymbalta is Duloxetine. The most common manufacturer of Cymbalta is Eli Lilly. Cymbalta has not been approved for children.
Zoloft comes in 25 mg, 50 mg, 100 mg tablets and 20-mg/ml oral concentrate. The generic name for Zoloft is Sertraline. The most common manufacturer of Zoloft is Pfizer. Zoloft has not been FDA approved for children suffering from depression, but Zoloft has been FDA approved for the treatment of OCD in children.
Both Cymbalta and Zoloft cannot be taken in combination with any monoamine oxidase inhibitors (MAOIs). Pain, fever and arthritis medications might cause easier bruising or bleeding when taking either Cymbalta or Zoloft. Before taking Cymbalta, you must advise your doctor if you are taking blood thinners or certain antibiotics. Before taking Zoloft, you must advise your doctor if you are taking blood thinners or heart rhythm medications.
The side effects of Cymbalta are generally the same as Zoloft. Some common side effects found in both medications include but are not limited to experiencing dry mouth, drowsiness, mild nausea, constipation, gas, insomnia, joint pain, weight changes, decreased sexual drive or impotence. The more serious effects shared by both include but are not limited to stomach pain, fever, appetite and weight fluctuation, stiff muscles, heart tremors, headache, memory problems, weakness, loss of coordination or shallow breathing.
Common over-the-counter medications such as cold or allergy medicines or sleep inducers as well as prescribed medications for seizures or anxiety can increase drowsiness often caused by both Cymbalta and Zoloft. Both Cymbalta and Zoloft are believed to cause harm to infants of pregnant or breastfeeding women. Conditions such as liver or kidney disease, seizures or epilepsy and bipolar disorder are extremely sensitive to the adverse effects of Zoloft.
What Are the Risks of Taking Cymbalta & Zoloft Together?
Medication is complicated business. Doctors go to school for years to learn how best to treat illnesses, but that doesn't mean they...
Lexapro Vs. Celexa for Anxiety
Celexa and Lexapro are medications frequently used in the treatment of depression and anxiety. Since the latter was created from the former,...
Celexa Vs. Cymbalta
Cymbalta (generic name duloxetine) and Celexa (generic name citalopram) are medications approved by the Food and Drug Administration to treat generalized anxiety...
Lexapro Vs. Zoloft
Lexapro and Zoloft are used to treat depression and anxiety. As both belong to the class of drugs known as Selective Serotonin...
Can Cymbalta & Lorazepam Be Taken Together?
Cymbalta is a prescription medication used to treat depression as well as generalized anxiety disorder, according to the Mayo Clinic. These two...
How to Stop Taking Zoloft
Zoloft is an antidepressant of the Selective Serotonin Reuptake Inhibitor (SSRI) class used to treat depression, obsessive-compulsive disorder, post-traumatic stress disorder and...
What Is the Best Time to Take Cymbalta?
Cymbalta (duloxetine HCI) s an antidepressant medication that is used to treat major depressive and general anxiety disorders. Cymbalta is a selective...