Signs & Symptoms of Chemical Imbalance of the Brain


Chemical imbalance in the brain is a medical condition which results when there are discrepancies in the levels of chemical compounds in the brain. There are medical conditions which are considered signs and symptoms of the chemical imbalance disease in the brain. It is also important to point out that, there is a lot of controversy within the medical community regarding the cause and effect of brain chemical imbalance.

What is Chemical Imbalance?

  • Chemical imbalance in the brain is one of the theories which seeks to explain causes of mental illness. This theory explains that neurotransmitter imbalance in the brain causes psychiatric conditions and mental illness. It was also discovered that certain neurotransmitters had too little activity in the brains of individuals suffering from schizophrenia. During the 1950s, monoamine oxadase inhibitors and tricyclic antidepressants were discovered to be helpful agents in treating depression. These discoveries were made by researcher Joseph Schildkraut; he published such findings in his research in 1965. Not everyone agrees that chemical imbalance in the brain causes mental illness, and the controversy still continues within the psychiatric discipline today.

How Does Chemical Imbalance Occur in the Brain?

  • The brain is surrounded by synaptic vesicles which cluster beneath the membrane of the brain. They often release neurotransmitters which are also known as endogenous chemicals. These chemicals relay and amplify brain signals transmitted between neutron and other cells of the brain. According to theories of chemical imbalance, abnormal levels or concentrations of these neurotransmitters in the brain leads to chemical imbalance in the brain.

What are the Symtoms of Chemical Imbalance?

  • Some doctors believe that attention deficit disorder is one of the early signs of chemical imbalance problem in the brain. ADHD is a medical condition which affects young children and adolescents. Such factors as inattentiveness, hyperactivity and impulsive behavior have been attributed to chemical imbalance in the brain. Not everyone believes in this, but many psychiatric physicians believe that these factors are early signs of mental illness resulting from abnormal levels of brain chemicals. Individuals with ADHD are often challenged by simple, everyday tasks.


  • Depression is another sign of chemical imbalance in the brain. There are also many other factors associated with depression such as hereditary or perfectionist behavior. Some doctors believe that one of the main causes of depression is the result of chemical imbalance in the brain. When imbalances occur in some neurotransmitters in the brain--such as serotonin, norepinephrine, and dopamine--such imbalance could lead into depression. These chemicals are like messengers that operate within the brain to influence the moods of people.


  • Diabetes is another disease often associated with chemical imbalance in the brain. Diabetes results from high concentrations of sugar in the blood. Although such condition and disease necessarily does not affect the brain, it has often been associated with chemical imbalance in the brain which in turn leads to other factors culminating in diabetes disease. Chemical imbalance in the brain may cause insulin imbalance in turn in the body. Insulin imbalance causes diabetes

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