Acetaminophen Side Effects

Acetaminophen is a popular over-the-counter drug that is used to reduce fevers and relieve pain. Although side effects are rare, chronic use, high dosages and interactions with other drugs can cause complications. Consult your physician or pharmacist if you have any concerns about taking acetaminophen.

Video of the Day

Common Side Effects

Some people who take acetaminophen may experience dizziness, fainting and trembling. Others may have pain in the side or lower back.

Rare Side Effects

Although rare, acetaminophen may cause yellow skin or eyes, bleeding and bruising, weakness, fatigue, discolored urine and black stools.


According to the Merck Manual, an overdose can cause nausea, vomiting, fatigue and even organ damage. Seek emergency care in the case of an overdose.

Organ Damage

If you suffer from hepatitis or other liver disease, acetaminophen can worsen symptoms. Acetaminophen, combined with alcohol abuse, can cause stomach bleeding. Acetaminophen can worsen symptoms associated with kidney disease.

Allergic Reaction

Although rare, some people may experience an allergic reaction. Seek emergency care immediately if there is a rash, swelling and difficulty breathing.

Drug Interactions

According to the Mayo Clinic, Cenocoumarol, Carbamazepine, Isoniazid, Phenytoin, Warfarin and Zidovudine can cause side effects when taken with acetaminophen. Consult your physician or pharmacist before combining these drugs.


Promoted By Zergnet
Is DIY in your DNA? Become part of our maker community.