- You should never apply Frontline to a cat or dog under the age of eight weeks. The medication is applied directly to the skin and can cause irritations and hyperactivity. Waiting until the kitten or puppy is a little older will lessen the chances of any side effects. It is also best not to use Frontline on a pregnant animal. You do not want to take the chance of the pesticides causing a problem for the unborn animal.
- In order for the pesticides not to be absorbed into a human being's skin, the individual administering the Frontline treatment should wear plastic gloves. These can be purchased relatively cheaply at any grocery store. It is also possible to place a plastic shopping bag over each hand if you do not have any plastic gloves available. Throw the plastic gloves or bags away after the treatment has been given.









