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What Happens to the Brain During a Migraine?

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From Quick Guide: Migraine Guide

Summary: A complex sequence of events occurs in the brain during a migraine, and the activation of these events occurs in the brain stem. Find out how a release of neurotransmitters leads to throbbing pain, nausea and sensitivity to light and noise with help from a board-certified neurologist in this free video on migraine headaches.

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By Alexander Mauskop
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Dr. Alexander Mauskop, MD FAAN, is the director and founder of the New York Headache Center in New York City. He is a board-certified neurologist with extensive experience in the field...read more

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Video Transcript

"I'm Alexander Mauskop. I'm Director of the New York Headache Center. What happens to a brain during a migraine is a complex sequence of events. There's activation of what we call migraine center which is located in the brain stem, and that's the earliest we can pick up on very sophisticated tests like CAT scan and MRI scans, where we can see a certain part of the brain lights up first and then sends messages to the other parts of the brain and there is a cascade of neurochemical events. There is a release of neurotransmitters, and cells talk to each other, and something leads to this very unpleasant experience of throbbing pain, nausea, sensitivity to light and noise. It's a very complex event, but we understand more and more every year as to exactly what happens, and maybe we can figure out where to stop this process, that is, maybe we can drop these chemical cascade of events at one place or another. And we have some drugs that are already doing that but there is a lot more to be learned, and hopefully we'll get much better treatments based on this understanding."

eHow Article: What Happens to the Brain During a Migraine?

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