Does an Enzyme's Shape Change During Catalysis?

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An enzyme's shape definitely changes during catalysis in a number of important ways. Find out if an enzyme's shape changes during catalysis with help from an experienced chemistry professional in this free video clip.

Part of the Video Series: Photosynthesis & Other Reactions
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Video Transcript

Hi, I'm Dan Weisenberger, and this is does an enzyme shape change during catalysis? The answer to that is yes, and as we show here in an enzyme catalyzed reaction, the enzyme interacts with the substrate to form an enzyme substrate complex where the chemistry occurs, thereby releasing the product, and the enzyme is free then to do another round of catalysis. Now, there is one model that is a classic model to explain changes in the enzyme shape during catalysis, and that's called the induced fit model, and if we have a substrate and an enzyme shown here, we can see that the enzyme and substrate are not complimentary in their shape, but as the substrate comes in closer and closer contact to the enzyme, the enzyme shape will conform, or change to that of the substrate will form the enzymes substrate complex shown here in order to facilitate the chemistry releasing the two products and the enzyme which had this confirmation during catalysis changes back to its original shape, and then can go through sequential rounds of catalysis. I'm Dan Weisenberger, and this is does an enzyme, does an enzyme shape change during catalysis.


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