How to Use Estriol Cream


Menopause can be one of the most stressful times in a woman’s life. As if just getting older wasn’t hard enough, her body undergoes numerous and sometimes severe changes. For many women, menopause can cause severe hormone changes, even leading to imbalances that leave her with symptoms ranging from the expected hot flashes to insomnia. Hormone imbalances can also affect a woman mentally, leaving her with low self-esteem and low libido. Estriol creams are used to supplement the hormone imbalances, easing the stress and suffering of menopause

Things You'll Need

  • Warm water
  • Hand soap
  • Towel
  • Estriol cream
  • Applicator

Internal Use

Wash your hands thoroughly with soap and warm water before handling the cream or the applicator. Dry your hands thoroughly on a clean towel.

Fill the applicator with the prescribed amount of estriol cream. Follow all product instructions for specific applicator directions.

Insert the applicator high into the vagina for best effectiveness. Depress the plunger on the applicator to release the medication.

Remove the applicator and wash with warm, soapy water. Do not use hot water to clean, as you can damage the applicator with water that is too hot.

Wash and dry your hands again before touching objects or another area of your body to avoid contamination.

Repeat per your doctor’s instructions; number of uses can vary by patient.

Topical Use

Wash and dry hands before using the cream.

Spread 1/4 tsp. of cream onto a soft, hairless area of your body. Rub the cream into the skin until it is almost completely absorbed.

Wash and dry your hands well before touching objects or another area of your body to avoid contamination.

Follow product or doctor instructions regarding number of uses per week. Rotate the application area every two to three uses to avoid saturating that area of the skin.

Tips & Warnings

  • Always follow your doctor's recommendations for use of any medication. Dosing and length of use can vary by person.
  • Never start a hormone treatment of any kind without first consulting your doctor. Do not use hormone supplements if you are pregnant, nursing or planning to become pregnant.
  • Use estriol cream for the shortest possible time at the lowest possible dosage to avoid serious side effects such as increased chance of heart disease, breast and uterine cancer and blood clots, among others.
  • Certain medicines, such as blood thinners or barbiturates, can react with estriol, limiting its effectiveness or creating allergic reactions. Make sure your doctor knows about all medications you are taking before he advises you about using estriol.
  • If you miss a dose of estriol cream, use it as soon as possible. If it is almost time for your next dose, wait to take the next one. Do not double dose.

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