How to Test for a Bone Marrow Match


Bone marrow transplant is a potential life-saving procedure for patients with blood-related cancers such as leukemia, lymphoma, and multiple myeloma. For many people, transplant is their only chance of a cure, but without a donor--someone whose immune system is genetically similar to theirs--they cannot undergo the procedure. The Be the Match Registry is an international database of people who are healthy and who consent to being bone marrow donors. If you would like to be a donor, simply follow the steps to join the Registry.

Things You'll Need

  • Computer
  • Donor registration kit
Woman in hospital with doctor
Woman in hospital with doctor (Image: Thomas Northcut/Digital Vision/Getty Images)

Getting Tested

Step 1

Confirm that you meet eligibility guidelines. You must be between the ages of 18 and 60 and healthy. You will not be able to donate bone marrow if you have heart disease, cancer, hepatitis, AIDS, or most autoimmune disorders. The minimum age is simply the legal age to consent, and the maximum age is drawn at 60 due to the effects of anesthesia on older people.

Woman having blood tested before becoming donor
Woman having blood tested before becoming donor (Image: Alexander Raths/iStock/Getty Images)

Step 2

Go to and click “Join the Registry.” You can fill out the form online, but if you prefer to talk to someone, put in your location to find the closest donor center.

Man researching online
Man researching online (Image: moodboard/moodboard/Getty Images)

Step 3

Send for the registration kit.

Woman getting registration kit
Woman getting registration kit (Image: Jacob Wackerhausen/iStock/Getty Images)

Step 4

Read the instructions in the kit and collect a cell sample by swabbing the inside of your mouth.

Woman getting mouth swab
Woman getting mouth swab (Image: Wavebreakmedia Ltd/Wavebreak Media/Getty Images)

Step 5

Return the sample to the address indicated in the kit.

Woman leaving mail for pick up
Woman leaving mail for pick up (Image: Johnny Chih-Chung Chang/iStock/Getty Images)

Step 6

Wait for news of a possible match from the Registry. This may happen almost immediately, or it may take many years. It is also possible that you will not match anyone, and therefore you will never be asked to donate. Unless you remove your name, you will be on the Registry until your 61st birthday. If you are identified as a potential donor, you will undergo more tests to confirm a match.

Couple reading mail
Couple reading mail (Image: Wavebreakmedia Ltd/Wavebreak Media/Getty Images)

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Tips & Warnings

  • Update the Registry if you move, if you have significant changes to your health, or if you no longer wish to be a bone marrow donor. Since the Registry is an international database, physicians from all over the world access it for potential donors. If the Registry is unaware of major changes to your situation and if you are found to be a possible match but are unable to donate, valuable time is wasted. The patient must then seek other options, such as more chemotherapy, to buy time until another potential donor is identified. However, as with many blood-related cancers, there just isn't enough time.


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