FedEx, the multinational shipping company based in Memphis, Tennessee, operates one of the world's largest cargo airlines, called FedEx Express. Like other airlines, FedEx hires pilots to fly both domestic and international routes. It has a fleet of more than 380 jet aircraft. The company holds its pilots to high educational standards -- FedEx requires all of its pilots to possess a minimum of a four-year college degree.

Go through flight training to get your pilot ratings. To fly for FedEx, a pilot must possess a minimum of an instrument rating, multiengine commercial pilot certificate and airline transport pilot certificate.

Obtain an entry-level flying job such as regional airline pilot, certified flight instructor or small-aircraft cargo pilot. According to Pilot Credentials, a website detailing FedEx's pilot qualifications, a pilot must have at least 1,500 hours as the pilot in command (captain or commander of record) of a fixed-wing aircraft.

Take the Federal Aviation Administration's flight engineer written test. You must have a flight engineer license before starting work as a FedEx pilot.

Go to the Pilot Credentials website and fill out the online applicant profile form. You will also need to pay the application fee, which was $50 as of October 2010.

Interview for the position. As with other pilot interviews, you must pass a written test and flight simulator test in addition to a standard job interview. You must also fill out an official job application before showing up for the interview.

Complete FedEx Express new hire training. Before starting your career as a FedEx pilot, you must pass aircraft familiarization and company procedure training. FedEx will inform candidates of the training location.