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It only takes a few hours to notice the differences at high elevation when coming from a lowland or coastal region. The air at high altitudes has less of everything: oxygen, pressure and humidity. It may surprise you how much your body misses these simple elements. It takes an average of 6 months for a person’s blood to adjust, and even longer for smokers. If your new location comes with a significant increase in elevation, there are a few things that will help you acclimate to high altitudes.