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Step 1
Rehydrate patients with giardiasis by oral or intravenous crystalloid solution. Also, examine close contacts of the patient for giardiasis.
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Step 2
Begin antimicrobial therapy to giardiasis in the bowel. Several regimens may be used but some effective alternatives such as atabrine and quinacrine are not available in the United States.
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Step 3
Use metronidazole as the preferred treatment in the United States. The cure rate is 85 to 90 percent with dizziness, headaches, a metallic taste and nausea as side effects. The adult dose is 250 mg and the pediatric dose is 5 mg/kg. Metronidazole is given orally for five to seven days.
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Step 4
Prescribe tinidazole outside the United States as a first-line choice with gastrointestinal upset as the only common side effect. The recommended adult dose is 2 g and the pediatric dosage is 50 mg/kg. Tinidazole is administered once.
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Step 5
Consider quinacrine as an effective alternative with a cure rate of 90 to 95 percent. The recommended adult dose is 100 mg and the pediatric dosage is 2 mg/kg. Quinacrine is given orally for five to seven days.










