How to Understand the Side Effects of Photodynamic Therapy

An emerging treatment for those diagnosed with lung or esophageal cancer is photodynamic therapy. Patients who receive photodynamic therapy are usually given an injection of the photosensitive drug Photofrin™ followed up by a series of laser light treatments. The combination of these 2 methods creates a chemical reaction that is lethal to cancerous cells, but can also cause a variety of side effects. Before you begin treatment, it's important to understand exactly what these effects are and how you can combat them.

Instructions

1. Expect to stay mostly indoors for 4 to 6 weeks. The major side effect of photodynamic therapy is extreme sensitivity to natural or bright artificial lights. This sensitivity will begin immediately after you receive your first treatment of Photofrin™.

2. Stock up on fever reducers. One of the side effects of photodynamic therapy is high internal temperatures, brought on by your body trying to fight off infection.

3. Have a steady supply of prunes or prune juice waiting at home. Constipation, although rare, can often occur in patients undergoing photodynamic therapy.

4. Be prepared for mild swelling or inflammation around the tumor site after the procedure. Your doctor may be able to prescribe medication to alleviate any discomfort, though this side effect usually lasts for only 1 to 2 days.

5. Understand that exposure to sunlight may cause your skin to become mildly discolored. This side effect has been reported in patients who only spent a few minutes in direct sunlight.

6. Ask your doctor if it's possible to take over-the-counter remedies for nausea, which is one of the more commonly reported side effects of photodynamic therapy.

Tips & Warnings

• Consider getting a second opinion as to whether photodynamic therapy is the best way to treat your cancer. You may discover alternative treatments better suited for your condition if you consult with another doctor.

• Remember that photodynamic therapy is never mandatory. As a patient, you have the right to determine whether you want to pursue this treatment or not.

• Contact your doctor immediately if your skin becomes red, swollen or blistered after undergoing photodynamic therapy.

• While it's natural to be apprehensive or concerned about potential side effects, there are numerous resources to help you better understand and get through the procedure. You can speak with your doctor to alleviate your fears, attend a support group with people who have already undergone photodynamic therapy or ask about the possibility of receiving anti-anxiety medication.