How Is Dostinex Metabolized?
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What is Dostinex?
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Dostinex, generically known as cabergoline, is a medication primarily used to treat patients whose bodies produce too much of the hormone prolactin. This especially can be used to help women stop producing, or produce less milk, while not being pregnant. Dostinex can also be used in some Parkinson's disease treatments, and for the treatment of prolactin-related tumor growths.
Liver
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Like most medications, the job of metabolizing the chemical and toxic components, and eliminating them from the body, falls on the liver. The liver is responsible for breaking these components down into smaller pieces called metabolites, which the body can then eliminate from your system.
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Enzymes
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The liver depends on a group of enzymes called P-450 enzymes to help break Dostinex down into smaller pieces through chemical reactions. Enzymes are proteins that are designed to catalyze (activate and speed up) these chemical reactions.
Elimination
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Once the enzymes have broken down Dostinex into metabolites, these remaining substances can be deposited into the urine. The metabolites are then flushed out of your body with the urine the next time you use the restroom.
Metabolism Issues
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A damaged liver can make it difficult for the body to metabolize Dostinex. Liver damage can occur for a variety of reasons, including alcohol abuse, cirrhosis and hepatitis. In those with compromised livers, Dostinex can quickly become toxic, as it takes the liver longer to metabolize the drug out of the bloodstream. Those with cardiac disease may also have issues metabolizing Dostinex, as most cardiac issues affect blood flow to the liver. Without adequate blood flow, it can be difficult for the liver to break down the medication.
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