How Does Triamterene Work?

  1. What is Triamterene?

    • Triamterene is a diuretic, which means that it helps the body eliminate excess fluid and sodium through the kidneys, usually resulting in increased urination, at least until the body adjusts. However, triamterene, also sold under the trade name Dyrenium, is unlike conventional diuretics in that it does not cause the body to flush out potassium with the extra water and sodium.

    What conditions does Triamterene treat?

    • A diuretic like triamterene is often used to treat fluid retention (also known as swelling or edema) caused by a range of medical conditions such as congenital heart failure, nephrosis of the kidneys, cirrhosis of the liver and high blood pressure. Dyrenium and other formulations of triamterene are prescription medications.

    How does it work?

    • Triamterene works by making the body produce more urine, thereby flushing excess fluid and sodium from the body through the kidneys, like most diuretics, except that it prevents potassium loss that other diuretics may cause. Triamterene blocks the re-absorption of sodium during filtration in the kidneys and the body produces more urine, which utilizes extra bodily fluid to wash sodium and water out of the kidneys.

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