How is Cellcept Used for Lupus?

Lupus

Lupus is an autoimmune disease. The immune system attacks the body, leaving it susceptible to infections and other diseases. Immunosuppressants, such as those used in organ transplants, can be effective in easing the affects of lupus. In some cases, it may push the disease into remission.

Cellcept

Cellcept (also known as Mycophenolate mofetil) is used to prevent rejection in organ transplants. It is also used in patients with lupus nephritis or kidney failure as well as other severe forms of lupus. Cellcept works to inhibit T and B cell functions. These lymphocytes cells are the most abundant in the blood stream. They are part of the of the white blood cell system. B cells are found in bone marrow while T cells begin in the marrow and migrate to the thymus.

Food and Drug Administration Approval

As of 2009, Cellcept has not been approved by the Food and Drug Administration (FDA) for use in the treatment of lupus. The FDA is in the process of reviewing studies, patient testimony and other data for possible approval. Clinical trials have already confirmed that Cellcept is effective in lupus nephritis or kidney failure. Other studies are being conducted to confirm the effectiveness in treating patients without kidney failure.

Side Effects

Cellcept has several side effects which range from mild discomfort to life threatening. These include diarrhea, low white blood cell count, some viral infections and certain types of cancer. The cancer risk is highlighted in long term users.

References

• ArthritisTreatment and Relief
• Clinical Trial
• National Institutes of Health