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Located off Ecuador's coast in South America, the Galapagos Islands have been made famous by Charles Darwin for their beauty and wildlife. Part of the country of Ecuador, port cities in the Galapagos include Santa Cruz, Baltra, North Seymour, San Cristobal, Espanola, Floreana, San Salvador, Isabella and Fernandina. Cruises sail in one-way and round-trip cruises from Ecuador, Puerto Rico, Spain and Morocco, and additional port stops include Spain's Canary Islands, Peru, Columbia and the Bahamas.