Can Prednisone Cause Diabetes in Dogs?

Long-term use of prednisone may increase the risk of diabetes for a dog.

Prednisone can be a helpful medication in managing a wide range of illnesses and diseases in dogs. However, even short-term use may cause side effects. Long-term use may increase the risk of diabetes in a dog. However, the benefits of prednisone may outweigh the risks.

Understanding Prednisone

Prednisone is a common medication in the class of drugs known as corticosteroids. Prednisone is a synthetic corticosteroid that is converted into prednisolone in the liver. Prednisolone aids in treating autoimmune conditions and inflammation in dogs, from relatively minor allergies to more serious conditions such as inflammatory bowel disease.

Side Effect: Diabetes

While considered a generally safe drug, prednisone can cause significant side effects. One possible risk of long-term use is diabetes. According to veterinarian Dr. Mike Richards, it is "widely accepted that prednisone may predispose dogs and cats to diabetes." Prednisone may cause insulin resistance, leading to diabetes. Prednisone may also complicate management of diabetes, since the drug can affect blood sugar levels.

Weighing Benefits and Risks

While prednisone may increase the risk of diabetes in dogs, the benefits of the drug's use may outweigh that risk. Some conditions that prednisone treats can be life-threatening or greatly decrease a dog's quality of life. Diabetes, while serious and potentially fatal if left untreated, can often be successfully managed through exercise, diet and insulin. As a dog owner, you should discuss the potential benefits and risks of using prednisone with your veterinarian.

References

• Pet Education: Corticosteroids (Steroids, Adrenocorticosteroids, Adrenocortical Hormones)
• Native Remedies: The Use of Prednisone in Dogs
• Vetinfo: Medication--Prednisone and other Corticosteroids
• Pet Education: Diabetes Mellitus in Dogs