Dilantin Vs. Generics
Dilantin, which has the generic name phenytoin, is an anti-seizure medication primarily used to treat epilepsy. While the generic drug is effective in treating epilepsy, patients have experienced problems, including seizures, when switching from the brand name to generic equivalents.
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History of Dilantin
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Dilantin was created in 1908, and its anti-seizure effects became known in 1938. It was approved by the Food and Drug Administration for treatment of seizures in 1953. It became one of the most widely used drugs for the treatment of epilepsy and remains widely prescribed.
Problems for Patients
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While the FDA says that generic equivalents of brand name drugs are the same, patients switching from Dilantin to generics have experienced problems, most notably increased numbers of seizures. A number of studies in medical journals have documented these adverse affects.
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Causes of Problems with Generic Dilantin Substitutes
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Medical experts are not certain why some patients experience problems when switching from Dilantin to generics. There is evidence that slightly different formulations and the release time of the medication into the bloodstream are the likely causes of increased seizures.
Insurance Issues
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Some insurance companies require pharmacists to switch to generic substitutes for Dilantin. However, the Epilepsy Foundation recommends that patients not be switched over to generics. Often, insurance companies will defer to a physician who requires a brand-name drug.
Conclusion
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If you are taking Dilantin or phenytoin, check with your doctor and pharmacist if you notice the look of the pill has changed or if you wish to switch to a generic. If your insurance company requires a shift to generic, you may want to appeal. The problems with switching between Dilantin and generics are well-known in the medical community, so your doctor and pharmacist should be able to give you good advice.
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