Side Effects of Sclerotherapy


For those suffering with varicose and spider veins, sclerotherapy may be a possible solution. The procedure involves injections that irritate the affected vein’s lining, resulting in inflammation, hardening and fading of the vein. Like any other medical procedure, however, this minimally invasive treatment is not without possible side effects.

Common Effects

The minimally invasive procedure is generally well tolerated. Common side effects include swelling at the site of the injections, bruising and minor bleeding.

More Serious Side Effects

More serious effects include hematomas (collection of blood beneath your skin), superficial thrombophlebitis (characterized by tenderness and warmth over the injection site) and vasovagal reflex (characterized by nausea, increased perspiration and palpitations).

Rare Side Effects

Rare side effects include deep venous thrombosis (blood clots that could cause serious health problems if they travel to your lungs), localized hypertrichosis (temporary increase in hair growing in the site of the injection) and vasospasm (spasm of the blood vessel, which can result in an ulcer).

What to Expect

Expect mild discomfort after the procedure. Most patients describe discomfort during the procedure as feeling similar to that of a bee sting. Afterward the discomfort is caused by the inflammation and hardening of the vein. Pain usually dissipates within one day.


Before undergoing sclerotherapy, tell your doctor if you have any medical conditions or allergies, or if you are pregnant or breast feeding.

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