What Was Retin-A Originally Used For?

What Was Retin-A Originally Used For? thumbnail
Retin-A was developed as an acne drug.

Retin-A, commonly used for the treatment of acne and wrinkles, has several strengths. The topical prescription drug has been used since the 1960s in dermatology.

  1. Retin-A's developer

    • Retin-A, which in generic form is named tretinoin, was originally developed by European researchers. However, it was Dr. Albert M. Kligman who found a formula of the drug tretinoin that could clear up acne without causing irritation, according to a Los Angeles Times obituary by Thomas H. Maugh II, published on February 24, 2010.

    Acne drug

    • Dr. Kligman developed Retin-A as an acne cream in 1967 at the University of Pennsylvania, according to a New York Times article by Edmund Andrews.

    Patent

    • Dr. Kilgman patented Retin-A in 1967. He and the University of Pennsylvania licensed the patent to Johnson & Johnson, which began selling Retin-A as an acne drug in 1971.

    Acne and wrinkle drug

    • While Dr. Kilgman was doing testing on acne patients for the Retin-A drug, many patients over 40 reported that the drug reduced the sign of wrinkles, according to the Los Angeles Times. Since 1971, Retin-A has been developed and used to treat acne.

    Treating wrinkles

    • Retin-A received a new patent in 1986 after Dr. Kilgman discovered the drug's wrinkle-fighting ability, according to a Boston Globe article by Joann Loviglio published on February 22, 2010.

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