Immune Mediated Skin Disease

Immune mediated skin disease--also known as autoimmune skin disease--is a condition in which the immune system attacks skin cells, leading to changes in function or appearance. There are many types of immune mediated skin diseases, each having its own prognosis and treatment.

  1. Types

    • Eczema, acne and psoriasis are among the more common immune mediated skin diseases and may pose less of a threat to overall health than diseases like scleroderma and discoid lupus. Other conditions in this category include vitiligo, dermatitis herpetiformis and rosacea.

    Cause

    • According to E Med TV, the exact cause of autoimmune skin disease is not known. A complex interaction between genetic and environmental factors is thought to play a role, though it is not known which pathogens or toxins actually trigger disease.

    Symptoms

    • Immune mediated skin diseases may cause changes in the texture, color or thickness of skin. Additional symptoms may include fever, rash, increased sun sensitivity and fatigue.

    Treatment

    • While each specific skin disease has its own set of treatments, the standard of care for autoimmune disease consists of treatment with immune suppressing drugs, according to Mayo Clinic. Corticosteroids and chemotherapy drugs like cyclophosphamide often help, while cosmetic procedures can improve the appearance of skin.

    Famous Ties

    • According to the ABC News website, actor and pop singer Michael Jackson suffered from both vitiligo and discoid lupus.

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