Dangerous Ammonia Levels in Humans & Animals

Ammonia is a normal component in human and animal physiology. Ammonia, however is toxic in high concentrations. High concentrations of ammonia in the blood signifies that the body is not effectively metabolizing and eliminating ammonia.

Ammonia's Role

Ammonia acts as a source of nitrogen for living systems. Nitrogen is required for the synthesis of amino acids, which act as the building blocks for protein.

A Healthy Balance

Ammonia is important for normal animal acid/base balance. To maintain a healthy acid/base balance in the body, excess ammonia is excreted in the urine.

Ineffective Metabolism

High concentrations of ammonia in the blood signifies that the body is not effectively metabolizing and eliminating ammonia.

Physiological Complications

Changes in behavior and consciousness are often exhibited when toxic levels of ammonia accumulate in the blood.

Elevated Ammonia Levels

Increased levels of ammonia may be present with:
Cirrhosis
Hepatic encephalopathy
Gastrointestinal bleeding --
Muscular exertion --

Drugs that may elevate ammonia levels include:
Alcohol
Barbiturates
Diuretics
Narcotics
Smoking

Decreased levels of ammonia may be present with:
Hypertension
Antibiotics (such as neomycin)

References

• Lab Tests Online: Ammonia