What Is an Alpha Beta Blocker?
Alpha-beta blockers treat high blood pressure (hypertension). These drugs work on both alpha and beta receptors, reducing the amount of blood pumped through the circulatory system. This reduces blood pressure levels.
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Function
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Alpha-beta blockers perform the same functions as alpha blockers and beta blockers. Alpha blockers reduce nerve impulses in the vascular system, which allows blood to flow more easily through the blood vessels. Beta-blockers block the effects of epinephrine on the heart, which slows the heartbeat and reduces the heart's workload.
Types
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Carvedilol and labetalol are examples of alpha-beta blockers, according to the American Heart Association. Coreg and Coreg CR are brand-name versions of carvedilol. Labetalol is marketed under the brand names Normodyne and Trandate.
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Effects
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Alpha-beta blocker side effects include insomnia, anxiety, tiredness, decreased libido and nervousness. Serious side effects include slow heartbeat, shortness of breath, fainting, swelling of the feet and ankles, nausea, loss of appetite, stomach pain, dark urine, depression and yellowing of the skin or eyes (jaundice).
Risks
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Alpha-beta blockers slow the heartbeat and reduce blood pressure, so it's possible for blood pressure levels to drop too low (hypotension). This may cause nausea, dizziness, fainting, blurred vision, difficulty concentrating, shallow breathing and fatigue. These drugs may interfere with your ability to operate heavy equipment or drive a motor vehicle.
Alternatives
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Several alternatives to alpha-beta blockers are available. Alpha-blockers and beta-blockers are available separately. Diuretics, calcium channel blockers, angiotensin receptor blockers, ACE inhibitors and vasodilators also treat hypertension.
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