What Are the Stages of Opiate Withdrawal?

Opiate withdrawal occurs in two distinctive stages---the acute withdrawal phase and post-acute withdrawal syndrome (PAWS). Acute withdrawal causes symptoms that are primarily physical in nature, such as diarrhea and fever, while PAWS mainly affects mental and emotional functioning.

  1. Gastrointestinal Symptoms

    • Gastrointestinal upset is among the first effects to be felt during opiate withdrawal. Symptoms may include diarrhea, intestinal cramping, nausea and vomiting.

    Flu-Like Symptoms

    • Those undergoing acute opiate withdrawal often experience runny nose, extreme fatigue, fever and chills.

    Joint and Muscle Pain

    • Because opiates are potent painkillers, withdrawal often causes rebound pain throughout the body. Flu-like muscle pains and sore joints are common and can range in severity from mild to debilitating.

    Anxiety and Insomnia

    • While they may appear secondary to physical symptoms, mental and emotional disturbances like anxiety, irritability and insomnia frequently occur during the acute withdrawal phase.

    Depression and PAWS

    • Depression and low mood may persist until the body begins to produce its own endorphins again. According to addictionsandrecovery.org, post-acute withdrawal syndrome (PAWS) can last more than two years and includes symptoms like depression, inability to concentrate and low energy.

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