What Are the Side Effects of Lisinop/HCTZ Tabs?

Lisinop/HCTZ is an abbreviation for a prescription medication that contains a combination of lisinopril and hydrochlorothiazide. Despite its effectiveness at lowering blood pressure levels in patients with hypertension, Lisinop/HCTZ tablets pose a risk for side effects in some patients.

  1. Types of Side Effects

    • The most common side effects of Lisinop/HCTZ tablets include dizziness, headaches, coughing, fatigue, and hypotension or low blood pressure.

    Time Frame

    • The side effects of Lisinop/HCTZ tablets are generally transient, diminishing as your body becomes acclimated to the effects of the medication, explains the U.S. National Library of Medicine.

    Drug Interactions

    • When combined with diuretics, like furosemide, or alcohol, Lisinop/HCTZ tablets pose an increased risk for low blood pressure, while the combination of diuretics and Lisinop/HCTZ tablets also has the potential to cause changes in the amount of potassium in your bloodstream. Because Lisinop/HCTZ tablets increases the risk of toxic effects from lithium, doctors rarely prescribe these medications for concurrent use.

    Risks

    • Lisinop/HCTZ tablets cause severe allergic reactions in some patients, such as anaphylactic shock, severe swelling of the face or esophagus, and potentially fatal skin rashes like Stevens-Johnson syndrome. Other risks associated with Lisinop/HCTZ tablets include liver failure and decreases of white blood cell counts, according to the U.S. National Library of Medicine.

    Considerations

    • Because Lisinop/HCTZ tablets have the potential to cause fetal death and miscarriages, doctors rarely prescribe the drug for use in pregnant women. If you have a history of angioedema, an inability to pass urine, asthma, congestive heart failure, diabetes, dehydration, heart disease, decreased blood sodium, kidney or liver disease, gout, or lupus, it may not be safe for you to take Lisinop/HCTZ tablets, warns the Mayo Clinic,

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