What Is a Heparin Bridge?

Heparin is an anticoagulant prescription medication that helps prevent blood clots. In October 2009, the FDA announced new methods to test the potency and purity of Heparin batches. These measures were taken because of a rash of adverse reactions the previous year.

Function

If you are on the anticoagulant Warfarin and need surgery, the medication will be discontinued to prevent excessive bleeding. But this may leave you vulnerable to blood clots. Heparin has less of a bleeding risk than Warfarin and can be used up until the surgery. This is called bridge therapy.

Time Frame

According to The Hemophilia and Thrombosis Center of Nevada, Warfarin should be discontinued three days before surgery. Heparin is then administered up until the day of surgery. Warfarin treatment can resume the next day.

Route of Administration

Heparin is injected intravenously or into the skin. Do not inject the medication into the muscle. MedlinePlus states the average dosage rate as varying between one to six times a day.

Side Effects

Call your doctor immediately if you experience unusual bleeding, fainting or vomiting.

Warning

Heparin may cause bleeding and isn't suitable for all patients. A Heparin bridge should only be used if you have a history of blood clots.

References

• The Hemophilia and Thrombosis Center of Nevada : Bridge Therapy
• MedlinePlus: Heparin
• FDA Public Health Alert: Change in Heparin USP Monograph