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Medication for PMS Irritability

PMS, or premenstrual syndrome, is a physical condition that usually recurs during a particular phase of the menstrual cycle. When PMS irritability cannot be managed with lifestyle changes, medications can be prescribed.

  1. Causes

    • According to Dr. Larry Altshuler in his book, "Balanced Healing," PMS may be caused by hormonal imbalances, dietary deficiencies and genetics. There may also be a deficiency in a brain neurotransmitter known as serotonin.

    Oral Contraceptives

    • Oral contraceptives can be used to relieve the symptoms of PMS. Oral contraceptives help by stopping ovulation and stabilizing hormonal swings.

    Antidepressants

    • According to the Mayo Clinic, selective serotonin reuptake inhibitors (SSRIs) have been successful in reducing the symptoms of PMS. SSRIs help reduce symptoms such as fatigue, sleep problems and food cravings.

    NSAIDs

    • Non-steroidal anti-inflammatory drugs (NSAIDs) can be beneficial if taken before or at the onset of menstruation. NSAIDs can help ease cramping and breast discomfort.

    Medroxyprogesterone acetate

    • Medroxyprogesterone acetate, Depo-Provera, is prescribed for severe PMS. The injection can be given to temporarily stop ovulation.

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