Ketoprofen is a medication available in both over-the-counter and prescription forms. As a non-steroidal anti-inflammatory drug, Ketoprofen is effective for relieving pain and inflammation.
Ketoprofen transdermal cream is a topical version of the non-steroidal anti-inflammatory medication. The cream was not FDA-approved as of November 2009 and was under clinical trials.
Ketoprofen medications inhibit the production of hormones known as prostaglandins and leukotrienes. Although doctors do not understand how, the reduction in these hormones caused by ketoprofen alleviates pain and inflammation.
During a 2000 study at the Heinrich-Heine-Universität in Dusseldorf, Germany, ketoprofen was established as effective for treating pain and inflammation when delivered through the skin rather than orally. A 2003 study at the University of California, San Diego (UCSD) School of Medicine found that ketoprofen transdermal creams were effective for alleviating muscle pain following exercise.
A 2009 study at the University Sapienza of Rome found that ketoprofen transdermal cream has the potential to make skin more sensitive to the sun, posing a risk for dermatitis or skin rashes.
While using ketoprofen cream, it is important that you apply sunscreen and avoid tanning due to the risk for sun sensitivity. The effectiveness of ketoprofen cream for treating pain caused by anything other than exercise is unknown.