What Are the Treatments for Canine Pemphigus Complex?
Canine Phemigus complex is a group of immune-mediated skin diseases that cause the dog's immune system to attack its own skin. The treatment will vary depending on which form of disease is present.
-
Pemphigus Foliaceus
-
Pemphigus foliaceus, the most common form, causes crusty lesions around the ears, eyes, groin, footpads and nose. Treatment is aimed at suppressing the immune system. Most cases are successfully treated using prednisone; azathioprine may be used along with prednisone in cases that do not respond well to prednisone alone.
Pemphigus Erythematosus
-
Pemphigus erythematosus, the second most common form, is closely related to pemphigus foliaceus; however, these lesions are confined to the face and ears. Topical ointments containing glucocorticoids are effective treatments, as are as vitamin E supplements.
-
Pemphigus Vulgaris
-
Pemphigus vulgaris, the most severe form, causes blisters on the groin, anus and vulva and inside the mouth and nose. Pemphigus vulgaris is difficult to manage and is often fatal. Treatment is the same as pemphigus foliaceus.
Pemphigus Vegetans
-
Pemphigus vegetans is extremely rare and little study has been done on the cause or treatment. Topical ointments containing glucocorticoids are an effective treatment.
Warning
-
Prednisone and azathioprine can cause health problems when used long term. Careful monitoring by your veterinarian, along with your cooperation, is necessary for the successful treatment of these diseases.
-
