What Are the Causes of Osteoporosis in Premenopausal Women?

Osteoporosis is a decrease in bone mass that occurs more often in women than in men. About one-fourth of all middle-aged and postmenopausal women have osteoporosis. Today, women as young as 25 are being diagnosed with this condition, once believed to be associated with aging.

  1. HIgher Risk Groups

    • Among premenopausal women, Caucasian and Asian women have the greatest risk of osteoporosis. Women who are underweight and have smaller frames have an increased chance for an earlier occurrence.

    Lifestyle Effects

    • Women whose lifestyle involves minimal physical activities or exercise or whose calcium intake is low are more likely than others to develop osteoporosis early. Long-term smoking (more than one pack a day for more than five years) and drinking alcoholic beverages in excess are also risk factors.

    Chronic Conditions

    • Many diseases and conditions are related to early diagnosis of osteoporosis. These include multiple sclerosis, thyroid problems, eating disorders, inflammatory bowel disease, Crohn's disease, celiac disease, lupus, kidney disease and rheumatoid arthritis.

    Medications

    • Medications connected to osteoporosis include steroidal medications, anticonvulsants, anticoagulants, drugs used to treat depression, immunosuppressants and thyroid medications.

    Personal History

    • Since heredity plays a role in osteoporosis, researchers are looking for genetic markers. Women are at greater premenopausal risk if relatives have been diagnosed with osteoporosis; have broken a bone of the wrist, hip, leg or spine in the absence of major trauma; or have lost more than one and a half inches in height. If you have a history of broken bones without trauma or have X-ray evidence of bone loss, your risk for premenopausal osteoporsis increases.

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