What Are Normal RF Quantitative Blood Test Results?

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High levels of auto-antibodies called rheumatoid factors (RF) indicate the presence of autoimmune disease. Rheumatoid arthritis, Sjogren’s syndrome and occasionally other autoimmune diseases cause a high RF count.

Blood is collected, and tested in a lab for RF.
Blood is collected, and tested in a lab for RF.

Levels

Target RF quantitative levels are measured in titers or units: 1:20 to 1:80 titers, and 14 to 60 u/ML represent normal RF levels. Lower RF levels rule out the possibility of rheumatoid arthritis and Sjogren’s syndrome.

RF quantitative levels are measure in titers or units.
RF quantitative levels are measure in titers or units.

Rheumatoid Arthritis

According to Quest Diagnostic website, the primary cause of a high RF result is rheumatoid arthritis. The doctor will order follow-up blood work to confirm or rule out the diagnosis.

The primary cause for a high RF result is rheumatoid arthritis.
The primary cause for a high RF result is rheumatoid arthritis.

Sjogren's Syndrome

Extremely high RF results indicate Sjogren’s syndrome. Symptoms of Sjogren’s syndrome include dry eyes and reduced saliva production. Sjogren’s syndrome is a symptom of more serious diseases such as lupus.

Extremely high RF results can indicate Sjogren's syndrome.
Extremely high RF results can indicate Sjogren's syndrome.

Autoimmune Disease

Autoimmune diseases can cause a high RF lab result. These diseases include hepatitis C, AIDS and mononucleosis.

Autoimmune diseases can cause a high RF lab result.
Autoimmune diseases can cause a high RF lab result.

Follow-Up

Your doctor will requests blood tests to diagnose or exclude rheumatoid arthritis and Sjogren’s syndrome. A test for anti-nuclear antibodies, along with a complete blood count (CBC), can confirm rheumatoid arthritis. Sjogren’s syndrome diagnosis is confirmed with a CBC, X-ray of the salivary glands, and ocular examination.

Your doctor will request further blood tests to diagnose and exclude certain ailments.
Your doctor will request further blood tests to diagnose and exclude certain ailments.

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