Is Ibuprofin for Inflammation?


Ibuprofen is the generic name of over-the-counter medicines such as Advil, Medipren, Genpril, Ibu, Midol, Motrin and Nuprin. As a non-steroidal anti-inflammatory drug, or NSAID, ibuprofen can be used to treat inflammation.

How It Works

  • NSAIDs work on enzymes called cyclooxygenases that enable the synthesis of molecules (prostaglandins), which impact inflammation.

Other NSAIDs

  • Other non-steroidal anti-inflammatory drugs include aspirin, indomethacin, nabumetone and naproxen, which is known by the brand name Aleve.

Drug Interactions

  • Ibuprofen may raise levels of lithium in the blood and could result in lithium toxicity. Blood pressure medicine may be less effective, since the bodily mechanism that ibuprofen affects is also involved in blood pressure regulation.


  • Ibuprofen can increase the risk of heart, circulatory, stomach and intestinal problems, and the longer the drug is taken, the greater the risk.

Other Uses

  • Besides use as an anti-inflammatory agent, ibuprofen can also reduce fever and relieve pain.

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