Duration of Treatment Spironolactone for Acne
Spironolactone, also known as Aldactone, is a synthetic steroid. Most commonly used for treating high blood pressure, the drug is sometimes also used for controlling hormonal acne. Considered a safe and effective hormone balancer, it is prescribed only to women for varying durations. Does this Spark an idea?
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Mechanism of Action
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Excess androgen hormones can trigger acne in females. Spironolactone belongs to a category of drugs called anti-androgens that prevent cells from absorbing these hormones. By reducing circulating levels of androgens, acne is brought under control.
Dosage
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For acne, spironolactone is usually given in a daily dose of 50 g to 100 g. The dosage may vary depending on the condition of acne in a patient.
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Duration
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Duration of treatment depends on the individual patient and the severity of her acne; it can be used for a week to a year or longer. Spironolactone is considered safe for long-term use, according to the result of a study.
Specific Usage
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Spironolactone is prescribed for a week only before the period, on a monthly basis, to women whose acne is limited to the premenstrual phase.
Spironolactone and Oral Contraceptives
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Prescribing oral contraceptives with spironolactone is common practice for treating acne. The drugs complement each other in calming the hormones responsible for acne.
Side Effects
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Menstrual irregularities and breast tenderness are the most common side effects associated with the drug. Patients with a history of kidney disease, breast and ovarian cancers are advised to stay away from spironolactone.
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