Side Effects of Salsalate
Salsalate is a prescription medication of the salicylate class used for treatment of rheumatic disorders, including osteoarthritis and rheumatoid arthritis.
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Dosing
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Salsalate is available in 500mg and 750mg tablets. A typical daily dosage is 3000mg, divided into either 1500mg twice per day or 1000mg three times per day. Exceeding 3000mg increases the risk of developing side effects.
Interactions
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Do not take salsalate with aspirin or other salicylate drugs, since it can increase the levels of salsalate in the blood stream to toxic levels. Taking salsalate with anticoagulants may lead to internal bleeding.
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Contraindications
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Salsalate is not recommended for pregnant women, since it may harm the developing fetus. Salsalate has not been adequately tested for use with children.
Side Effects
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Common side effects of salsalate include tinnitus, impaired hearing, rash, vertigo, nausea and other gastrointestinal disturbances.
Warning
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Individuals who have the flu, chicken pox or a similar illness may develop Reye's syndrome if salsalate or another salicylate medication is taken.
Reye's syndrome causes swelling of the brain and fatty liver, and if not successfully treated within a couple days of onset, is fatal.
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