Relora Side Effects

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Relora's stress-eliminating effect may help induce sleep.
Relora's stress-eliminating effect may help induce sleep. (Image: Dave & Les Jacobs/Blend Images/Getty Images)

Relora, a dietary supplement believed to reduce stress and aid in weight loss, contains a bark extract of the magnolia and phellodendron plants. These herbs combined have demonstrated an ability to reduce stress in evidence-based clinical trials when taken as a supplement. Relora is made of natural ingredients and side effects are uncommon, but they can occur.

Listed Side Effects

The manufacturers of Relora, Next Pharmaceuticals, note that some people may experience mild drowsiness for the first couple of days. The manufacturers state that pregnant or lactating women should not use Relora. There are no known drug interactions, though the U.S. Food and Drug Administration does not require supplement manufacturers to test for drug interactions during development, so interactions might still occur.

Additional Studies

In a study published in a 2008 issue of Nutrition Journal, 38 participants were given a Relora supplement or placebo for six weeks. Two participants taking Relora dropped out of the study due to side effects. One reported heartburn, shaking hands, numb lips, sexual dysfunction and thyroid problems. The second participant experienced tiredness and headaches. Another study, published in a 2013 issue of the Journal of the International Society of Sports Nutrition, examined 56 participants' response to Relora supplements. Over the four-week study, no side effects were noted.

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