Pliva 563 Side Effects


Cyclobenzaprine hydrochloride 10 mg tablets are marked Pliva on one side and 563 on the other. This medication is prescribed to treat pain and muscle spasms caused by injuries such as sprains and strains. Many side effects are possible, some serious.


Cyclobenzaprine is a muscle relaxant which blocks nerve impulses sent from the injured body part to the brain, thus preventing pain sensations.

Common Side Effects

Common cyclobenzaprine side effects include blurred vision, dizziness, drowsiness, dry mouth or throat, lack of appetite, abdominal pain, nausea, constipation or diarrhea, gas and muscle weakness.


Because of the drowsiness side effect, patients may not be able to drive or do other activities requiring alertness while taking cyclobenzaprine.

Drug Interactions

Other drugs worsen the drowsiness effect of cyclobenzaprine. These include alcohol, anti-anxiety and anti-depression medications, cold and allergy medications, narcotics, sleeping pills and tranquilizers.


Rarely, serious complications can result from taking cyclobenzaprine. Serious side effects include heart attack or stroke, allergic reactions, seizures, liver damage, hallucinations and depression. An overdose can be fatal.

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