Tylenol P.M. Side Effects

Tylenol PM contains two ingredients: diphenhydraminen HCL to help you sleep and acetaminophen to relieve pain. Consult with a doctor before taking any sleep aids in order to avoid potential side effects.

  1. Grogginess and Restlessness

    • According to tylenol.com, drowsiness is expected when you take Tylenol PM in order to help you fall asleep, but next-day grogginess is not a common side effect. Also, you may experience restlessness from diphenhydraminen HCL. These side effects will cease when you stop taking Tylenol PM.

    Dependency

    • Tylenol.com advises that you not take Tylenol PM for more than two weeks unless your doctor recommends otherwise. However, tylenol.com states that the diphenhydraminen HCL contained in Tylenol PM is not habit-forming.

    Alcohol

    • Tylenol PM contains acetaminophen, which can cause liver damage if you take it with alcohol. Tylenol.com recommends that you consult a doctor before using Tylenol PM if you drink more than three alcoholic beverages a day.

    Drug Interactions

    • Do not take other pain relievers that contain acetaminophen with Tylenol PM, as you risk an overdose. Also, according to tylenol.com, you should not take Tylenol PM with tranquilizers or sedatives.

    Overdose Symptoms

    • According to drugs.com, you should tell a doctor about any unusual symptoms that you suspect are associated with Tylenol PM. These include dry mouth, hypotension, dizziness, depression, heart palpitations, tachycardia, nausea, skin rash and urinary retention.

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