Breast Cancer Medication and Fertility Treatments

Medications designed to treat breast cancer can often lead to infertility. However, doctors have made great advances in fertility treatments for breast cancer patients.

  1. Causes

    • Certain chemotherapy drugs carry higher risks of causing infertility by damaging the patient's eggs and/or interfering with the production of hormones that stimulate ovulation. One of the most common drugs used to treat breast cancer is Cytoxan, a type of alkylating agent known to adversely affect fertility.

    Considerations

    • Some patients are at higher risk of chemotherapy-induced infertility than others. Women over age 35 and those requiring high doses of medication face the greatest risk.

    Time Frame

    • Breast cancer patients concerned about fertility should discuss options with a doctor before beginning chemotherapy. Many women take proactive steps to preserve fertility prior to exposure to the cancer-treating drugs.

    Pre-Chemotherapy Options

    • The most common pre-treatment options include freezing of embryos, eggs or ovarian tissue.

    Options During Chemotherapy

    • Various scientific studies are currently under way involving drugs such as GnRH-a (Gonadotropin-releasing hormone analog) that can halt ovulation during treatment, possibly protecting the eggs from harm.

    Options After Chemotherapy

    • Fertility options after successful eradication of breast cancer include use of standard fertility drugs; use of one's own frozen embryos, eggs or ovarian tissues; use of donor eggs or embryos; or surrogacy.

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