- Depo-Provera is a progestin-only form of birth control that prevents pregnancy by preventing ovulation and changing cervical mucus to prevent fertilization.
- According to Planned Parenthood, Depo Provera is more than 99 percent effective when used correctly. It is one of the most effective forms of birth control.
- The most common side effect of the Depo-Provero shot is irregular bleeding. Most women have no periods after a year of being on the shot. Some experience heavier periods and spotting between periods. Other less common side effects include weight gain, nausea, change in libido, fatigue and depression.
- According to Familydoctor.org, Depo-Provera should not be used for more than two years unless you are unable to take other types of birth control. Long-term use can cause calcium in your bones to deplete, which can lead to osteoporosis.
- Because the Depo-Provera shot stays in your system for three months, there is no way to get the medication out of system early. It can also take 9 to 12 months to get pregnant after you stop taking the Depo-Provera shot, according to Planned Parenthood.
- Women who are pregnant or who have cancer of the reproductive organs, unexplained vaginal bleeding, liver disease or a history of blood clots or stroke should not use Depo-Provera.











