What Is Lodine 400 mg Used For?


Lodine is a brand name for the medication etodolac, a non-steroidal anti-inflammatory drug (NSAID) prescribed to treat acute and chronic pain. Lodine is available in a variety of strengths, including tablets of 400 mg in regular and extended-release versions.


Like other NSAIDs, such as ibuprofen and naproxen, Lodine reduces levels of hormones that cause inflammation, thus decreasing pain and tenderness.


Lodine is primarily prescribed to relieve joint pain, inflammation, swelling and stiffness of osteoarthritis and rheumatoid arthritis. Although the U.S. Food and Drug Administration (FDA) has not approved Lodine for use by children, doctors often prescribe it to treat juvenile arthritis.

Other Uses

Lodine is useful for reducing pain caused by tendinitis, bursitis, muscle strain and pain in the back, feet, legs or bones.

Off-Label Uses

Besides juvenile arthritis, other common off-label uses for Lodine include relieving pain associated with fibromyalgia, gout, lupus and migraine headaches.


Recommended dosage depends on the condition for which the patient uses Lodine. Maximum daily dosage is 1000 mg, although some doctors allow 1200 mg for arthritis treatment.

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