Side Effects of Ibuprofen 600
Ibuprofen is the active ingredient in a number of brand name pain-relievers such as Advil, Motrin and Nuprin. It is classified as a non-steroidal anti-inflammatory (NSAID). In addition to relieving pain, ibuprofen is also effective at reducing fever.
Gastrointestinal problems are the most noted side effects of ibuprofen and other NSAIDs. But, as with any medication, other problems may occur.
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Gastrointestinal/Hepatic Effects
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Ulceration in the gastric lining, GI bleeding, GI perforation, heartburn and nausea occur in three to nine percent of patients taking ibuprofen. Constipation, diarrhea, flatulence and indigestion occur less often. Hepatitis has been reported, but is rare, occurring in less than one percent of patients.
Dermatologic Effects
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Skin rash, itching, or hives have been reported. A serious allergic response known as Stevens-Johnson syndrome has been noted in rare cases.
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Effects on the Blood
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Ibuprofen may cause thinning of blood by inhibiting platelet action. Disruption of normal red and white blood cell function may also occur, but is quite rare.
Central Nervous and Musculoskeletal System Effects
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Headache, nervousness and fatigue have been reported with ibuprofen use, as well as drowsiness, dizziness and confusion. Ringing of the ears may also occur with extended use.
Metabolic, Endocrine and Renal Effects
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Fluid retention is the most noted metabolic effect of ibuprofen and other NSAIDs. In patients with poor kidney function, ibuprofen may worsen the condition.
Other Useful Information and Precautions
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Ibuprofen should be taken with a full glass of water and food in the stomach. Patients taking anticoagulants such as warfarin or heparin should not take ibuprofen without consulting a physician, as ibuprofen can increase the blood-thinning effects of these medications. Because ibuprofen is related to aspirin, patients with aspirin allergy should avoid ibuprofen and other NSAIDs. Certain people with a history of asthma and aspirin sensitivity may experience rare but serious respiratory reactions with ibuprofen or other NSAIDs.
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