Types of Lupus Disease

Lupus is a chronic, autoimmune disease that causes the body's immune system to malfunction and attack normal cells. Lupus affects about 1.5 million Americans, and about 90 percent of lupus patients are female. Learn more about the most common types of lupus disease here.

  1. Systemic Lupus Erythematosus

    • Systemic lupus erythematosus (SLE) is the most common and serious type of lupus. Systemic lupus can cause pulmonary hypertension, or high blood pressure in the lungs, as well as inflammation of the kidneys, nervous system and brain.

    Cutaneous Lupus Erythematosus

    • Cutaneous lupus erythematosus (CLE) typically affects the skin, causing a scaly, red, raised rash. One common rash associated with CLE is the "butterfly rash," which is spread across the cheeks and over the bridge of the nose.

    Drug-Induced Lupus Erythematosus

    • Drug-induced lupus is triggered by a reaction to certain prescription drugs, particularly anti-seizure, hypertension and acne medications. Symptoms typically disappear within six months of stopping the medication, and typically include fever, rash and inflammation of the sac surrounding the heart.

    Neonatal Lupus

    • Neonatal lupus is a rare type of lupus that occurs among infants born to mothers who suffer from the condition. Symptoms usually disappear within several months, and include low blood cell counts, skin rashes and liver problems.

    Causes

    • While the exact cause of lupus is unknown, researchers believe possible factors include genetics, hormones, race, stress and infections.

    Medications

    • Lupus treatment varies according to the type of lupus and the severity of the symptoms. Typical medications used to treat lupus include anti-inflammatory, corticosteroid, antimalarial, anticoagulant and immunosuppressive medications.

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