HCG Shot Side Effects

HCG, also known as human chorionic gonadotropin, is generally injected under the skin or into a muscle. It is often used in conjunction with a fertility drug, such as Femara or Clomid, to encourage ovulation in infertility patients. HCG can also be used to help with weight loss. As with most treatments, there are several side effects to using the shot.

  1. Multiple Pregnancies

    • When being used to treat infertility, HCG can increase the chance of becoming pregnant with twins, triplets, quadruplets or even more babies.

    Ovarian Hyperstimulation Syndrome

    • Ovarian Hyperstimulation Syndrome, or HSS, is one of the most serious side effects to a HCG shot. Ovaries become overstimulated with follicles, which can case severe pelvic pain, stomach pain, swelling, nausea and vomiting and shortness of breath.

    Digestive Side Effects

    • HCG (as well as OHSS) can cause nausea, vomiting, diarrhea and decreased urination.

    Early Puberty Onset

    • For young boys using HCG shots, there is a risk that it can trigger an early onset of puberty. Symptoms of this are hair growth, acne, sweating and a deepened voice.

    Blood Clots

    • HCG shots can cause blood clots, which can be life-threatening. If you experience any of the following symptoms, call your doctor immediately--extreme dizziness, severe headaches, pain, confusion, numbness or tingling in your arms or legs.

    Other Side Effects

    • Other side effects of HCG shots are water weight gain, headaches, depression, irritability, breast tenderness and swelling at the injection site.

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